Annual independent film festival in Philadelphia, screening features, documentaries, shorts and animation from around the world. Among its thematic highlights are "Cinema of the Muslim Worlds", which in 2003 was covered by the Wall Street Journal; "Danger After Dark," an internationally-renowned celebration of genre films; and the annual Festival of Independents, a regional filmmaking showcase.

Annual indie film festival in Eerie, featuring outstanding independent films in the digital medium.

Annual film festival in Pittsburgh since 1981, and the oldest film festival in the area. Generally a two week long celebration showcasing films made in Pittsburgh, documentaries, independent American cinema, shorts, international and even restored classic films with live music. They also host parties throughout the city, a photo auction, visiting filmmakers, informal post-screening discussions and more.

Annual independent environmental film festival in Milford, designed to support the artistic expression of independent films, and to promote the region’s clean air and water, abundant wildlife, natural beauty and the entities that protect them. The festival was founded based in part on the recognition of the area’s history as both the birthplace of the American conservation movement and a popular filmmaking location.

Annual film festival in Philadelphia, focused on the genres of Action, Adventure, Suspense and Asian Action.

Annual festival held in October since 1985, showcasing gay, lesbian, bisexual, and transgendered writers, directors, actors and their work. Film lovers from Pennsylvania, Ohio, West Virginia, and the surrounding areas attend this ten day event, including exciting social events at some of Pittsburgh's most popular gay and gay-friendly nightspots.

Annual horror film festival in Eerie, established in 2004 in an effort to provide more opportunities and exposure for filmmakers, screenwriters and video game developers working within the horror, science fiction and suspense genres.

Annual film festival in Butler, celebrating films of the silent era through the 1950's, hosted by Creepy Classics and Scary Monsters.

Annual festival in Philadelphia since 1995, featuring a "rainbow" of GLBT film and video images from around the world. The festival screens as many as 200 features, documentaries and shorts, and attracts an attendance of over 25,000, making it the largest gay and lesbian film festival in the Eastern U.S.